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Pharmaceutical

Intermediate

Sl No. Intermediate Name CAS No. API
1 6-(2-Propenyl)-Ergoline-8-Carboxylic Acid 81409-74-7 Cabergoline
2 1,6-di-(tert-butoxycarbonyl)-8beta-hydroxymethyl-ergoline 1075250-75-7 Cabergoline
3 1,6-di-(tert-butoxycarbonyl)-ergoline-8beta-carboxylic acid 1075250-76-8 Cabergoline
4 4-(Trifluoromethoxy)aniline 461-82-5 Riluzole
5 Tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 571188-59-5 Ribociclib / Palbociclib
6 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one 1016636-76-2 Palbociclib
7 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid 1211443-58-1 Ribociclib
8 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide 1211443-61-6 Ribociclib
9 8-Amino-6-Methoxyquinoline 90-52-8 Primaquine
10 4-Quinolinol, 7-methoxy-8-methyl-2-[4-(1-methylethyl)-2-thiazolyl] 923289-21-8 Deldeprevir, Simeprevir, Neceprevir
11 9-Benxyloxy-3-(2-Chloro ethyl)-2-methyl pyrido[1,2-a]pyrimidine-4-one 147687-17-0 Paliperidone
12 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 130049-82-0 Paliperidone
13 1-(2,2-diMethoxyethyl)-5-Methoxy-6-(Methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid 1335210-23-5 Dolutegravir /bictogravir
14 DiMethyl 3-(benzyloxy)-1-(2,2-diMethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate 1246616-66-9 Dolutegravir /bictogravir
15 DiMethyl 3-(benzyloxy)-1-(2,2-diMethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate 1357289-08-7 Dolutegravir /bictogravir
16 4,6-Dichloro-5-methoxy Pyrimidine (4,6-DCMP) 5018-38-2 Sulphadoxine
17 2,6-Diamino-4-chloropyrimidine 156-83-2 Minoxidil
18 Guanine 73-40-5
19 Hydroquinidine 1,4-phthalazinediyl diether ((DHQD)2PHAL) 140853-10-7 Catalyst for Sharpless asymmetric dihydroxylation
20 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone 22246-18-0 Aripiprazole
21 (S)-(−)-2-Aminomethyl-1-ethylpyrrolidine 22795-99-9 leosulpride
22 Ethyl N-(2.3-dichloro-6-nitrobenzyl)glycine 70380-50-6 ANGRELIDE
23 2-NITROPHENYL SULPHENYL CHLORIDE 7669-54-7
24 Glutaric acid 110-94-1
25 Glutaric anhydride 108-55-4
26 O-Benzylhydroxylamine HCL 2687-43-6
27 3-((dimethylamino)methyl)-9-methyl-2,3-dihydro-1H-carbazol-4(9H)-one hydrochloride 119812-29-2 Ondansetron
28 4-Pyridinecarboxaldehyde (Isonicotinaldehyde) 872-85-5 donepezil
29 4′-Methyl-2-cyanobiphenyl (OTBN) 114472-53-1 Valsartan
30 Tamsulosin 106133-20-4 Tamsulosin
31 5-[(2R)-2-Aminopropyl]-2-methoxybenzenesulfonamide 112101-81-2 Tamsulosin
32 5-Acetonyl-2-methoxybenzenesulfonamide 116091-63-5 Tamsulosin
33 Ramelteon 196597-26-9 Ramelteon
34 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one 196597-78-1 Ramelteon
35 (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine Hydrochloride 196597-81-6 Ramelteon
36 (E)-2-(1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile 196597-79-2 Ramelteon
37 (4,5-Dibromo-1,2,6,7-tertahydro-8H-indeno[5,4-b]furan-8-one) 196597-77-0 Ramelteon
38 (S)-2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine Hcl 196597-85-0 Ramelteon
39 N-((N-Methyl-N-((2-isopropyl-4-thiazolyl)methyl)amino)carbonyl)-L-valine methyl ester 154248-99-4 Ritonavir
40 (S,Z)-5-Amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one 156732-13-7 Ritonavir
41 (2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane 144164-11-4 Ritonavir
42 [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic acid 1,1-dimethylethyl ester 144163-85-9 Ritonavir
43 (S)-2-(3-((2-Isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoic acid 154212-61-0 Ritonavir
44 (2-isopropylthiazol-4-yl)-N-methylmethanamine 1185167-55-8 Ritonavir
45 (S,Z)-5-Amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one 156732-13-7 Lopinavir
46 N-[(1S,2S,4S)-4-Amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-2-(2,6 dimethylphenoxy)acetamide 192725-49-8 Lopinavir
47 [(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic acid 1,1-dimethylethyl ester 144163-85-9 Lopinavir
48 (4S)-4-(N, N-dibenzylamino)-3-oxo-5-phenylpentanonitrile 156732-12-6 Lopinavir
49 (2S,3S,5S)-2-(2,6-Dimethylphenoxyacetyl)amino-3-hydroxy-5-(tert-butoxycarbonyl)amino-1,6 diphenylhexane 192725-45-4 Lopinavir
50 (2S,3S,5S)-5-amino-2-(dibenzylamino)- 1,6-diphenylhexan-3-ol 156732-15-9 Lopinavir
51 4′-Methyl-2-cyanobiphenyl (OTBN) 114472-53-1 Valsartan/Olmesartan
52 Bromo OTBN 114772-54-2 Valsartan/Olmesartan
53 Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate 144689-93-0 Olmesartan
54 2-bromo-1-(3-chlorophenyl)propan-1-one 34911-51-8 Bupropion
55 2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4- (4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl) methyl)piperazin-1-yl)benzoic acid 1235865-77-6 Venetoclax
56 tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate 1628047-84-6 Venetoclax
57 1H-Pyrrolo[2,3-b]pyridin-5-ol 98549-88-3 Venetoclax
58 Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 1235865-75-4 Venetoclax

API

SI No. API Name CAS No. Therapeutic Category
1 Hydroxypinacolone Retinoate, all-trans retinoic acid, 1-hydroxy-3,3-dimethyl-2-butanone ester 893412-73-2 Vitamin A
2 Riluzole 1744-22-5 Sclerosis
3 Cabergoline 81409-90-7 Dopamine Receptor
4 Chlorothymol-ih 89-68-9
5 Dibucaine hydrochloride-USP 103639-04-9
6 Oxybutynin chloride – USP 1508-65-2
7 Trihexyphenidyl hydrochloride-BP/IP 52-49-3
8 Paliperidone 144598-75-4
9 Aripiprazole -IP/USP 129722-12-9
10 Resperidone 106266-062
11 Nortriptyline Hydrochloride 894-71-3
12 Angrelide 68475-42-3
13 Tamsulosin 106133-20-4
14 Ramelteon 196597-26-9
15 Palbociclib 571190-30-2
16 Ribociclib 1211441-98-3
17 Minoxidil 38304-91-5
18 Minoxidil Sulphate 83701-22-8
19 Trazodone hydrochloride 19794-93-5
20 Escitalopram Oxalate 219861-08-2
21 Escitalopram 128196-01-0
22 Topiramate 97240-79-4